Plasma total cholesterol also decreased after four months in the 1,000mcg/day group. Two-hour glucose values were also significantly lower after both two and four months (four-month values: placebo, 12.3mmol/L 1,000mcg/day chromium, 10.5mmol/L). Fasting glucose levels were lower in the 1,000mcg/day chromium group than placebo (chromium, 7.1mmol/l placebo, 8.8mmol/L ). In a randomised, placebo-controlled trial, 180 Chinese adults with type II diabetes took either 200mcg/day chromium picolinate, 1,000mcg/day or placebo. Anderson, PhD, and colleagues at the US Department of Agriculture, Beltsville Human Nutrition Research Center, in conjunction with Beijing Medical University Hospital. A seminal study in this area was conducted in 1997 by Richard A. There is evidence that suggests chromium may be useful in the management of diabetes, but at levels much higher than the daily amount recommended to stave off deficiency conditions. Additionally, work has been done on chromium's utility in depression and cholesterol management. Because of chromium's role in insulin activity, researchers have looked at using the trace mineral to help diabetics control their blood-sugar levels. It also activates insulin receptor kinase, leading to increased insulin sensitivity. Chromium increases the number of insulin receptors on the cell membrane and enhances insulin binding to cells. Ĭhromium appears to make insulin function more efficiently by enhancing the uptake of glucose from the blood into the cell. Some researchers have long believed the rising rate of type II diabetes is due in part to chromium depletion in the food supply. However, food processing strips chromium from foods, particularly when grains and sugars are refined. Cereals, particularly high-bran cereals, contribute variable but potentially important amounts of chromium. Few foods are good chromium sources, a recent USDA analysis found. The recent establishment of a daily chromium requirement of 35mcg for men and 25mcg for women by the Institute of Medicine in the US has raised its profile. Send all comments or additions to: The JANUARY 2003 Issue of Functional Foods & NutraceuticalsĪs this trace mineral begins its integration into foods, conclusive research remains to be conducted on toxicity and optimal dosage amounts for various conditions.
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